The objectives of this research are to understand the economic importance of border bridges on the U.S.-Canada economies, especially involving the various US states proximate to the Provinces of Ontario, and to simulate various the U.S.-Canada border bridge policy and security scenarios. To this end, we combined a novel bi-national highway network data with a freight flow dataset using ports of entry (POE) via highway border crossings. Through several sub-procedures, the US and Canada highway systems are integrated into a single network dataset. This contributes to providing hierarchical economic impacts at the state/province or lower levels of the two countries. Complex and disaggregated models can lead to a better understanding of how economic impacts resulting from traffic pattern changes on the border bridges can affect the local economies of neighboring states in the United States.